I am certainly no expert, and 700-calorie smoothies aside, my understanding is that naturally-occurring fructose is effectively quite distinct from refined sugars:Quote from atticus:
You seem to make a distinction between refined sugars and naturally-occurring fructose. Is it because the (smoothie) is nutrient-dense? A 700-calorie smoothie is likely to be 50% calories in fructose.
Yes, it is nutritionally-dense, but packed with sugar. Excluding the vitamins and minerals and you just ate 3 Snickers bars. I realize the comparison seems like a stretch, but that's an assault on your pancreas.
...Fructose found in fruits and vegetables is slowly absorbed into the blood stream, its absorption blunted by the soluble fibre naturally found in these foods. In contrast, HFCS and crystalline fructose disrupt liver metabolism, which, along with excess glucose, spikes blood sugar levels and exhausts our pancreas. It is the overwhelming amounts of fructose and ensuing spike in blood sugar levels that are derailing our body's metabolism and immune system in ways we don't fully understand...
http://www.digestivedistress.com/fructose-and-its-impact
