Zinc vs Covid-19
- Thread starter Wallet
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Taking 30mg Zinc Gluconate daily
50mg D3 daily
800mg Quercetin Bromelian twice daily.
1000mg C twice daily.
Edit 15ml, straight elderberry concentrate (no additives) mixed in with a bottle of water daily.
I plan to continue this until family can get antibody tested. We think we were exposed early on with very very light symptoms. Quarantined ourselves for the 14 days. Operating/social distancing like we are vulnerable until we can get tested.
Living in rural areas tis’ easy to isolate.
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I am not sure what the advised Quercetin : Zinc ratio is supposed to be, I am going to research it. My Gluconate pill is 50 mg and the daily Quercetin is 500 mg, so looks like your ratio is 3 times higher than mine.
Well, I have found something more interesting:
"A South Korean research paper has demonstrated in Vitro that by increasing the Zinc concentration in cellular cytoplasm, that viral replication is inhibited. As intracellular levels of Zinc are increased the inhibition of viral replication can reach 100% according to charts within the paper.
The researchers used two antimalarial drugs which are Ionophores. Ionophores are molecules that can carry a charged ion like Zinc across a cellular membrane. South Korea has been treating high risk, Critically I’ll COVID-19 patients with the drug Hydroxychloroquine. It is likely the single clinical reason that South Korea has the lowest death rate in the world for COVID-19 victims of 0.6% Hydroxychloroquine is a pharmaceutical drug that requires a prescription.
However there is a nutritional supplement called Quercetin that is a Zinc Chelator and Ionophore and requires no prescription. It’s interesting that there has been a great deal of research done on the ability of Elderberries as and antiviral agent. And Elderberries, Red Wine and Blueberries all three have high amounts of Quercetin. It may be likely that the high Quercetin content of these foods is the reason for their measurable anti-viral properties.
So what would be better than supplementing Zinc and Quercetin together to elevate intracellular Zinc levels in order to inhibit viral replication? Since there have been no Clinical Trials of this supplement regimen then dosages are your best guess. But even increasing Zinc to levels that result in a thirty percent inhibition seems like a major advantage to the patient, and may be enough to tip the struggle in your favour."
https://nutritionalpharmacology.wordpress.com/2020/03/21/combating-covid-19-with-zinc-and-quercetin/
"A South Korean research paper has demonstrated in Vitro that by increasing the Zinc concentration in cellular cytoplasm, that viral replication is inhibited. As intracellular levels of Zinc are increased the inhibition of viral replication can reach 100% according to charts within the paper.
The researchers used two antimalarial drugs which are Ionophores. Ionophores are molecules that can carry a charged ion like Zinc across a cellular membrane. South Korea has been treating high risk, Critically I’ll COVID-19 patients with the drug Hydroxychloroquine. It is likely the single clinical reason that South Korea has the lowest death rate in the world for COVID-19 victims of 0.6% Hydroxychloroquine is a pharmaceutical drug that requires a prescription.
However there is a nutritional supplement called Quercetin that is a Zinc Chelator and Ionophore and requires no prescription. It’s interesting that there has been a great deal of research done on the ability of Elderberries as and antiviral agent. And Elderberries, Red Wine and Blueberries all three have high amounts of Quercetin. It may be likely that the high Quercetin content of these foods is the reason for their measurable anti-viral properties.
So what would be better than supplementing Zinc and Quercetin together to elevate intracellular Zinc levels in order to inhibit viral replication? Since there have been no Clinical Trials of this supplement regimen then dosages are your best guess. But even increasing Zinc to levels that result in a thirty percent inhibition seems like a major advantage to the patient, and may be enough to tip the struggle in your favour."
https://nutritionalpharmacology.wordpress.com/2020/03/21/combating-covid-19-with-zinc-and-quercetin/
I’m dosing as the bottle reads. Would be very interested in what you find.
If I remember correctly the Canadian group doing the Quercetin trials were using very high doses. Something like 5g for average person, not exactly sure of the mg per kilo ratio but it was a lot. They modeled the dosage after their Ebola and Zika studies. But here again they are going at the virus after the patient is sick and not as a preventative.
Should have book marked the links i ran across, i’ll try to find and post them.
I am not really finding anything. As the quote says in post #74, because there aren't really any clinical trials about Quercetin, your dosage is your best guess. So I guess there are 2 approaches based on circumstances:
1. Single person, plenty of pills available: Your best guess is trying to max out of the biggest still not dangerous dosage, so in elemental Zinc 40 mg and whatever it says on Quercetin, I think 1000 mg or a bit more. Specially if this is an older person or in the endangered group (high BP, diabetes, fat, smoker)
2. Multiple people in a home, limited pills available: Let's say you have 4 people in the family and only 1-1 bottle of each Zinc and Q. Let's assume 2 kids and no new pills coming in the next 5 or so days. I would do the math and divide the pills accordingly up to 7 days, the kids getting smaller dosages. And order more, but a good 5 days treatment should have a very desirable effect once symptoms start.
1. Single person, plenty of pills available: Your best guess is trying to max out of the biggest still not dangerous dosage, so in elemental Zinc 40 mg and whatever it says on Quercetin, I think 1000 mg or a bit more. Specially if this is an older person or in the endangered group (high BP, diabetes, fat, smoker)
2. Multiple people in a home, limited pills available: Let's say you have 4 people in the family and only 1-1 bottle of each Zinc and Q. Let's assume 2 kids and no new pills coming in the next 5 or so days. I would do the math and divide the pills accordingly up to 7 days, the kids getting smaller dosages. And order more, but a good 5 days treatment should have a very desirable effect once symptoms start.
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https://greenstarsproject.org/2020/03/27/quercetin-a-treatment-for-coronavirus/
Quercetin – a naturally occurring zinc ionophore.
Quercetin is a flavonoid (a type of polyphenol) that’s present in a variety of edible plants – from herbs like cilantro and dill, to veggies and fruit such as onion, kale and cranberries, with the highest concentration found in capers. Quercetin was demonstrated to be a zinc ionophore in 2014.
“Dietary plant polyphenols such as the flavonoids quercetin (QCT) and epigallocatechin-gallate act as antioxidants and as signaling molecules. Remarkably, the activities of numerous enzymes that are targeted by polyphenols are dependent on zinc. We have previously shown that these polyphenols chelate zinc cations and hypothesized that these flavonoids might be also acting as zinc ionophores, transporting zinc cations through the plasma membrane.”
If HCQ proves to be effective in treating COVID-19 then it’s possible that quercetin in our diet may also be protective (while avoiding the side effects of HCQ). But that’s also predicated on quercetin having a similar effect to HCQ in patients and again, medicine is complex.
Quercetin – other chances that it may be helpful in treating COVID-19
Quercetin and plants that contain it have a certain following for treatment of various conditions – for example, capers are used in Iranian Traditional Medicine. Taking a look at the scientific studies carried out specifically on quercetin, here are some highlights:
Quercetin – a naturally occurring zinc ionophore.
Quercetin is a flavonoid (a type of polyphenol) that’s present in a variety of edible plants – from herbs like cilantro and dill, to veggies and fruit such as onion, kale and cranberries, with the highest concentration found in capers. Quercetin was demonstrated to be a zinc ionophore in 2014.
“Dietary plant polyphenols such as the flavonoids quercetin (QCT) and epigallocatechin-gallate act as antioxidants and as signaling molecules. Remarkably, the activities of numerous enzymes that are targeted by polyphenols are dependent on zinc. We have previously shown that these polyphenols chelate zinc cations and hypothesized that these flavonoids might be also acting as zinc ionophores, transporting zinc cations through the plasma membrane.”
If HCQ proves to be effective in treating COVID-19 then it’s possible that quercetin in our diet may also be protective (while avoiding the side effects of HCQ). But that’s also predicated on quercetin having a similar effect to HCQ in patients and again, medicine is complex.
Quercetin – other chances that it may be helpful in treating COVID-19
Quercetin and plants that contain it have a certain following for treatment of various conditions – for example, capers are used in Iranian Traditional Medicine. Taking a look at the scientific studies carried out specifically on quercetin, here are some highlights:
- In 2015 it was reported that quercetin inhibits entry of the influenza A and the H5N1 virus to cells in vitro.
- Quercetin was also found to inhibit adhesion of the human respiratory syncytial virus (hRSV).
- Researchers from Oak Ridge National Lab used the world’s most powerful supercomputer, SUMMIT, to look for small molecules that might inhibit the COVID-19 spike protein from interacting with human cells and interestingly, quercetin is fifth on that list.
- This is not a peer-reviewed scientific publication but Leo Galland also recommends quercetin, but via a different mechanism (mTOR modulation). Incidentally, his other recommendations can also be obtained from food sources: curcumin (turmeric), rosmarinic acid (rosemary, sage, oregano), resveratrol (red wine and grapes), and elderberry.
So Trump finally mentioned Zinc. Compared to this thread, the government is a good 3 weeks behind the times and research.
On CNN Sanjay Gupta was on and Cuomo the lesser asked him about Zinc. He knew exactly shit about it, although he did say that the safety profile is OK. Then he switched the topic. Let's give them another 2 weeks before more people and doctors start to use it and get the picture.
In the main time I am preaching the gospel and among my friends and relatives they are getting quercetin while it is possible.
Here is another Gupta getting confused about Zinc:
http://www.msnbc.com/mtp-daily/watch/dr-gupta-trump-s-zinc-recommendation-is-mystifying-81803845737
On CNN Sanjay Gupta was on and Cuomo the lesser asked him about Zinc. He knew exactly shit about it, although he did say that the safety profile is OK. Then he switched the topic. Let's give them another 2 weeks before more people and doctors start to use it and get the picture.
In the main time I am preaching the gospel and among my friends and relatives they are getting quercetin while it is possible.
Here is another Gupta getting confused about Zinc:
http://www.msnbc.com/mtp-daily/watch/dr-gupta-trump-s-zinc-recommendation-is-mystifying-81803845737