But not nearly as big a difference as running any company and running a government entity of any kind!
I should have completed my thought (I blame multi-tasking with toddler bedtime):
I would wager running a fortune 50 firm makes you as qualified to be president as being a senator or state governor.
You can say that Rex tillerson is an example of a failure and that would only be because he can't fill his despartment - trump won't allow anyone who signed the never trump pledge to work in the administration (and much of the diplomatic community was thus barred from working in the state dept).