Lupus patients are not getting sick from CCP virus

Dr. Oz Explains A Breaking News Study Out Of France Today.

https://detroit.cbslocal.com/2020/04/10/dr-oz-explains-a-breaking-news-study-out-of-france-today/

French doctor, Didier Raoult met with France’s Premier Emmanuel Macron last night to present a new paper that studied 1,061 COVID-19 patients that were treated early with hydroxchloroquine and azithromycin (z-pac). He found that those on this drug protocol met with 92% excellent outcomes (they were free of the virus within 10 days). He also found the drug protocol to be very safe for patients with low side effects, and that there was a correlation with the amount of hydroxychloroquine found in the blood and success rates.

This study looks at early treatment. At best it’s showing a mild benefit and that benefit probably extends to healthy patients that were never going to get to the stage where they needed hospitalization.
 
This study looks at early treatment. At best it’s showing a mild benefit and that benefit probably extends to healthy patients that were never going to get to the stage where they needed hospitalization.
There are large studies being done everywhere. We will know soon enough if this treatment lowers mortality enough to save the economy from total collapse.
 
Dr. Oz Explains A Breaking News Study Out Of France Today.

https://detroit.cbslocal.com/2020/04/10/dr-oz-explains-a-breaking-news-study-out-of-france-today/

French doctor, Didier Raoult met with France’s Premier Emmanuel Macron last night to present a new paper that studied 1,061 COVID-19 patients that were treated early with hydroxchloroquine and azithromycin (z-pac). He found that those on this drug protocol met with 92% excellent outcomes (they were free of the virus within 10 days). He also found the drug protocol to be very safe for patients with low side effects, and that there was a correlation with the amount of hydroxychloroquine found in the blood and success rates.

It should be noted that "Dr. Roult" out of Marseille has fabricated medical papers hyping results -- even before COVID-19. His initial COVID-19 studies promoting hydroxchloroquine with a "100% treatment success rate" were dropped by medical journals as not meeting standards when it was found out that he simply ignored the patients where it did not work - including the 10% in the study group that died.

As I stated earlier - "Dr. Oz is a quack. Anyone who relies on him or anyone he brings onto his show for medical guidance is not thinking rationally"

There are many proper medical trials of hydroxchloroquine and azithromycin underway in the U.S. right now. We should wait for complete medical results before passing any type of judgment. I will what I stated earlier - the initial results of a NY trial on severely ill patients does not appear to be promising (less than a week in based on unverified medical commentary) but there at least needs to be another month of testing to provide a sizable sample of patients with full results before any conclusions can be made.

The following article outlines in detail the locations of studies being undertaken in the U.S. for treatment of COVID-19 with hydroxchloroquine and azithromycin.

---------------------------- portion of article below --------------------

Six of the centers that responded said it would take months to get study results: Henry Ford Health System in Michigan; University of Washington; Baylor Scott & White Health in Texas; Vanderbilt University in Tennessee; Bassett Healthcare; and Duke University in North Carolina.

For example, doctors conducting a large clinical trial at Henry Ford are aiming for more than 3,000 participants and say it will take about four months to conduct their study. Researchers running a trial at New York University and the University of Washington say they'll have around 2,000 study subjects and expect to have results in June or July.

Two centers said they could have results within weeks. The University of Minnesota is doing a study to see if hydroxychloroquine can help prevent people from becoming infected with coronavirus. They say they could have results May 7, or possibly even earlier. (Here's a story about a physician who's a study subject in that trial.)

Rutgers University said they could have initial results by late April or early May on their study of whether hydroxychloroquine alone, or in combination with azithromycin, might help treat coronavirus.
The reason a clinical trial can't be done in days is because the universities need to recruit study subjects, who then need to take the pills for a period of time. Doctors need to analyze the results.

That all takes time -- even when doctors are moving at lightning speed because of the pandemic.
"We need rigorous science, we need the right science," said Dr. Ruanne Barnabas, the principal investigator at the University of Washington. "This is the most urgent study we've ever worked on and we're moving quickly to get results."

The other seven centers conducting hydroxychloroquine studies for coronavirus are: Columbia University in New York; Intermountain Health Care, Inc. in Utah; the University of Pennsylvania; Washington University in St. Louis; Providence Health in Oregon; ProgenaBiome, a laboratory in California and Sanofi, a pharmaceutical company.
 
Yeh, the studies are all over the place and the methodologies are all over the place too.

Those who promote hydroxy are actually promoting a regimen which includes hydroxy plus azythromycin plus zinc at 225 mg. But I don't see the azythromycin in some studies and I don't see the zinc being added in others. The whole idea behind the proposed regimen is that the hydroxy acts as an ionophore to transfer the zinc ion through the cell membrane and on to the receptor site where the virus would like to attach its sorry arse if the zinc were not already there. So the studies need to be more than just about the hydroxy.

And then there are reports about how a swedish study pooped out but they were missing some of the "ingredients" and they reported that they started using chloroquine because they ran out of hydrochloroquine which is a derivative but a different animal. And I dont think they had zinc in the treatment either.

As I have said before, my hopes are quite bounded. I just want to see if there is an edge there because most treatments for serious conditions involve stacking together little edges until you have a meaningful edge. So it is not a show stopper for me if it is not how some are hyping it.

Also some of the studies determine success based on not dying, others on not needing to be intubated and some base on how long there was a measurable viral load before the drug cleared it. But viral presence is not necessarily the meaningful measure. You could - for example- have a seasonal flu that is a bitch and wont go away for weeks but nevertheless it never reached a critical level- which is possible with Covid too. Any drug that keeps covid from progressing to critical would be valuable even if it did not clear the virus from your system for weeks. And some of the tests differ too because they are picking viral shedding rather than live virus which can go on for weeks.

Anyway. Researchers need to tighten up on what needs to researched and agree upon the parameters and then see what's what. Too much variation between studies right now.

There are now more comprehensive studies underway in the U.S. and world-wide regarding COVID-19 being treated with hydroxchloroquine and azithromycin. It will take several weeks for proper results to be determined. Hopefully the treatment does provide some edge. The unverified, early medical commentary makes it appear that the treatment is not promising on severely ill patients but more promising on patients who are mildly afflicted --- but we need to wait for proper results before drawing any conclusions.

In the meantime, the trials and results should be left to medical professionals --- unverified treatments should not be hyped by politicians and media pundits as a "cure".

One issue with hydroxchloroquine is its impact on patients with pre-existing heart conditions or those who take drugs such as metformin.
French officials report heart incidents in experimental coronavirus treatments with hydroxychloroquine
https://thehill.com/policy/internat...icials-report-heart-incidents-in-experimental
 
One issue with hydroxchloroquine is its impact on patients with pre-existing heart conditions or those who take drugs such as metformin.
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And they are only taking metformin because they have diabetes and we are already learning that diabetes - with or without metformin- is a very high risk factor. That is a partial explanation of why the virus is doing so much damage in low-income and/or black communities- which just coincidentally have an undiagnosed epidemic of diabetes. Ditto for obesity which of course is also highly, highly correlated with diabetes.

As discussed, there needs to be studies but well-designed studies. You can't have a research test group of just 20 people and then come back and say a drug did or did not work and oh by the way five had diabetes, 12 were overweight and two had heart disease. Too many moving parts. And those researchers promoting the drug cannot stack the research the other way, where they compare a test group of 20 patients (where you need 200) of healthy young people with no underlying causes to a control group that includes people with conditions.

Finding out that something does not work is as important as finding out that it does. We just need to speed that process up and not get married to any one approach prematurely. It should not be done recklessly but neither should it be done at the speed of government.
 
Israeli COVID-19 treatment shows 100% survival rate - preliminary data

Not only have all the patients survived, according to Pluristem, but four of them showed improvement in respiratory parameters.

Six critically ill coronavirus patients in Israel who are considered high-risk for mortality have been treated with Pluristem’s placenta-based cell-therapy product and survived, according to preliminary data provided by the Haifa-based company.
The patients were treated at three different Israeli medical centers for one week under the country’s compassionate use program and were suffering from acute respiratory failure and inflammatory complications associated with COVID-19. Four of the patients also demonstrated failure of other organ systems, including cardiovascular and kidney failure.
 
Israeli COVID-19 treatment shows 100% survival rate - preliminary data

Not only have all the patients survived, according to Pluristem, but four of them showed improvement in respiratory parameters.

Six critically ill coronavirus patients in Israel who are considered high-risk for mortality have been treated with Pluristem’s placenta-based cell-therapy product and survived, according to preliminary data provided by the Haifa-based company.
The patients were treated at three different Israeli medical centers for one week under the country’s compassionate use program and were suffering from acute respiratory failure and inflammatory complications associated with COVID-19. Four of the patients also demonstrated failure of other organ systems, including cardiovascular and kidney failure.

I will note that the treatment involved very expensive placenta-based cell-therapy not hydroxchloroquine and azithromycin

The sample set of patients that is so small it is not possible to draw any meaningful conclusions. Pluristem, a Haifa-based company has been hyping this in every media source possible - serving to drive up their stock (PSTI). To me it looks more like a pump & dump scheme.
 
There are large studies being done everywhere. We will know soon enough if this treatment lowers mortality enough to save the economy from total collapse.

I get Donald Trump is very focused on the chloroquine approach but that does not mean there are not other approaches and meds and vaccines being tested right now.

The chloroquine issue has become more of a cult movement than anything else. Its crazy this has become such a singular focus.

Yes, there are good studies going on right now for this and other drugs, and existing vaccines, and plasma therapies too.
 
I will note that the treatment involved very expensive placenta-based cell-therapy not hydroxchloroquine and azithromycin

The sample set of patients that is so small it is not possible to draw any meaningful conclusions. Pluristem, a Haifa-based company has been hyping this in every media source possible - serving to drive up their stock (PSTI). To me it looks more like a pump & dump scheme.
That was the first thing that crossed my mind too lol.
Its amazing how many people buy into it too. They may or may not be on to something...
but this is classic and laughable. I don't even have to look, I already know there'll be no shares to short.



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It gets even better when you look at their latest numbers.
Am I reading that right? $23,000 in revenue and 15.7M shares outstanding.


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Buy buy buy!:p
 
I spent some time in malaria areas. I took hydroxychloroquine but you had to have a checkup to get a prescription. They definitely didn't just hand it out. There were concerns and the stuff was not without side effects like vertigo and a few other things.
 
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