Once you've determined stats in your favor, you do just have to shut up your brain and trade the setups with reckless abandon. The odds in your favor will take care of the profits.
I mindlessly placed orders based on my setups and every now and then after my position's on I see something that makes me go "Doh!", and I take the loss and move on. I could sit around and try to filter for everything in a quest for "perfection", but the end result of that is usually lower odds.
I'll post this again and again, says it all regarding profitable trading:
http://www.cornixtrading.com/2012/07/rats-vs-yale-students-randomness-psychology/
Assuming even R:R, a 60% win rate allows you to trade for a living.
A 52% win rate allows you to gradually transfer your entire account to your broker.
BTW, here's another gem from Cornix (bold emphasis is mine):
"Moral of the story: traders usually have rules for a reason. They develop rules when away from the markets, in a calm state of mind. We should watch ourselves not to be fooled by randomness and caught in second-guessing rules
just because single trades do this or that. Thatâs market playing the mind games with us, because we lose the sense of a border between real-time and hindsight, when actively trade."