Regeneron has sat out this whole Covid fight. Is it time?
Regeneron’s Covid-19 Antibody Protects Household Contacts From Infection
April 12, 2021 8:33 am ET
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The antibody treatment could offer protection to people who live with individuals who have been infected with Covid-19.
Trials of Covid-19 antibody treatments have turned up consistently positive data in recent months, but those benefits have mostly been seen in a narrow group of people who were already sick.
On Monday,
Regeneron changed that. It released data on two studies that, with the U.S. Food and Drug Administration’s nod, could expand the usage of Regeneron’s antibody therapy.
Antibody therapies for Covid-19 from a handful of drug companies have demonstrated their ability to dramatically reduce the risk of hospitalization and death in patients with mild to moderate illness at high risk of progressing to severe disease. Regeneron’s (ticker: REGN) antibody cocktail, known as REGEN-COV, reduced hospitalization and death by 70% in
high-risk nonhospitalized patients.
The cocktail received emergency use authorization in November.
Now, Regenron says that new data shows that REGEN-COV can prevent infection, too.
In a Phase 3 trial run jointly with the National Institute of Allergy and Infectious Diseases at the National Institutes of Health, the antibody cocktail was given to uninfected people living in the same household as recently infected people. Subcutaneous injections of REGEN-COV reduced the risk of symptomatic infection in those household contacts by 81%.
People in the trial who received the antibody therapy but did get infected anyway had symptoms for less time than those in the placebo group who got sick.
“With more than 60,000 Americans continuing to be diagnosed with COVID-19 every day, the REGEN-COV antibody cocktail may help provide immediate protection to unvaccinated people who are exposed to the virus,” said Regeneron’s chief scientific officer, Dr. George Yancopoulos, in a statement.
The company said it would ask the FDA to expand the emergency use authorization of REGEN-COV to include use to prevent Covid-19. Regeneron shares were up 1.3% in premarket trading.
The stock is down 1.6% so far this year, and down 8.1% over the past 12 months.
In addition to the prevention trial, Regeneron also on Monday announced the results of another Phase 3 trial of subcutaneously administered REGEN-COV run with the NIAID, this one in recently infected asymptomatic
Covid-19 patients.The company said that the antibody reduced the risk of progressing to symptomatic Covid-19 by 31%. If the patient was not symptomatic by day three, they were 76% less likely to develop symptoms by day 29.
Analysts currently expect $2.4 billion in sales of REGEN-COV in 2021. The company has signed two separate deals to provide doses of the therapy to the U.S. government this year, one for $260 million and one for up to $2.6 billion.
A study in March showed that the treatment’s efficacy was the same at a lower 1,200 mg dose level than at the 2,400 mg dose level authorized by the FDA. The FDA has not yet updated its emergency-use authorization to allow for the lower dosing level.
At the lower dosing level, Regeneron would be able to supply 1.25 million doses of the therapy. Under the terms of its January contract with the U.S. government, Regeneron
would earn$2.6 billion if it could supply those doses by June 30.
Wow.
Hospitals were staying away because it was too complicated... & expensive. I'm going to take a wild guess here that there is something about this REGN cocktail that is going to come back into favor especially with these variants. I saw that the South Africa I believe is knocking down the Pfizer I believe Vax... (stoned when I was watching the news) But one of the vaccines is not working well against one of the variants, that's a very bad sign for our future.
Lets say a variant comes around that makes the vaccines useless as they are now I bet this REGN cocktail comes back huge.
Your downside would seem limited but... there is a bet here with the Gov and what hey are willing to spend....
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Dick's lands firmer, longer estimates from Argus ahead of reopening period
- Argus boosts its love of Dick's Sporting Goods(NYSE:DKS)to $92 from $82.
- "While there is uncertainty about what the economy might look like in three years, we are modeling approximately 4% sales growth, an operating margin of 7% and very modest share repurchases."
- Argus raising its Q1 EPS estimate to an erect $0.81 from $0.75 on a slightly higher firmer sales forecast. The FY22 EPS estimate goes to $5.07 from $5.00.
- The firm doesn't have a formal estimate for FY24, but believes that DKS can earn approximately $6.00 per share.
- Argus also issues an improved outlook for the possibility of stoney having sex. Raising their
- assessment rating on that to Medium from Medium-Low at the start of the pandemic.

- estimates on Dick's here.