As I saw a few doctors say on the news...
HCL may work if provided early...
Links to the studies are provide in the meta study..
I have no desire to debate this... read studies and tell us why they are flawed.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534595/
Timing of HCQ provision
It was striking that 100% of the 11 studies which provided HCQ early in the disease on an outpatient basis showed positive results. In two of the studies [
9,
10], the benefit was only a trend. However, the effects were clinically important. In the study of Mitjà et al. [
9], resolution of symptoms was decreased from 12 to 10 days; in that of Skipper et al. [
10], the rate of hospitalization was decreased by 60%. It is likely that if the studies had higher power, statistical significance would have been reached. In the 32 other studies, HCQ was provided on an inpatient basis in patients with more advanced disease. The studies were divided into early, late and ICU administration. Early provision—within 48 hours of admission—showed 67% (6/9) of the studies to have positive efficacy. Later provision—after 48 hours' admission or in the ICU—found positive efficacy in 40% (2/5). Thus, from 100% for early outpatient, to 67% for early hospital to 40% for later hospital provision, there appears to be a relationship with time of initiation of treatment, with better results observed the earlier HCQ is provided.
