How does it work: as an oxidizing agent massive amounts, i.e., 5-150 grams, intravenously, for certain pathological conditions, if allowed to run in rapidly (20 gauge needle), acts as a ââ¬ÅFlash Oxidizerââ¬Â and may correct the condition in minutes. It can be a reducing agent. It neutralized toxins, viruses and histamine. The more serious the condition, the more C is required.
It appears that Vitamin C acts as a reducing agent, an oxidizing agent, an anti-clotting agent, an antihistamine, and as an anti-infective agent.
He summarized the function of C in poliomyelitis:
1. Virus destruction.
2. Dehydrates the brain and the spinal cord safely.
3. Supports and normalized the stressed adrenal glands.
4. It preserves the lining of the central canal and maintains more regular spacing and less crowding of ependymal cells (surface cells of the spinal cord).
Ascorbic acid enters all cells. It ââ¬Åproceeds to take up the protein coats being manufactured by the virus nucleic acid, thus preventing the assembly of new virus units.ââ¬Â Cells expand, rupture and die, but there is no virus particles available to enter and infect new cells. If a virus has invaded a cell, the Vitamin C contributes to its breakdown to adenosine deaminase, which converts adenosine to inosine. Purines are formed which are catabolized (broken down) and cannot be used to make more virus nucleic acid.
Viral nucleic acid has a protein coat which protects this parasite as it rides the blood or lymph highway to gain specific cell entry. [Larson] it is possible that if the ascorbic acid can remove that protective protein coat in the blood stream or in the cells, the white cell phagocytes and immune globulin could then neutralize these vulnerable virus particles.
I like this from Dr. Klenner: ââ¬ÅAscorbic acid also joins with the available virus protein, making a new macromolecule which acts as the repressor factor.ââ¬Â (interferon?) Multiplication of new virus bodies is inhibited.
He summarizes the study of Lojkin, (1937), who discovered the inactivation of one virus was due to a specific intermediate product formed in the course of the oxidation of C but needed the stimulation of copper ions. It is a peroxide and is decomposed as rapidly as it is formed. This study indicates why Vitamin C works better in the body and not the test tube. Every function of the body requires enzymes, some vitamins and some minerals to act as coenzymes. If enough Vitamin C is supplied, the enzyme system that breaks down invading viruses and bacteria, will be able to do its job properly. Quote: ââ¬ÅUnless the white blood cells are saturated with ascorbic acid, they are like soldiers without bullets.ââ¬Â
Vitamin C in vitro at body temperature inactivates certain toxins at an unbelievable rate. Back in 1938 some researchers [Klegler] placed Vitamin C in test tubes with toxins. After incubation for 48 hours the toxins were not lethal to mice when injected. The more toxin in the tube, the faster the C disappears. ââ¬ÅThe rate of disappearance of the C in toxin and ordinary broth was more striking the greater the concentration of Vitamin C.ââ¬Â Dr. Klenner concluded: ââ¬ÅThe degree of neutralization in a virus infection will be in proportion to the concentration of the vitamin and the length of time which it is employed.ââ¬Â
This has been Dr. Klennerââ¬â¢s main complaint: failure to benefit from Vitamin C use is usually due to inadequate amounts being used for too short a period of time.
Vitamin C combines directly with the toxin/virus. This new compound is oxidized by Vitamin C; the toxin/virus and the Vitamin C are destroyed. This must be why C has to be continued after the apparent cure.
It acts as a respiratory catalyst, aiding cellular respiration by acting as a hydrogen transport. The liver has a better chance of detoxifying the blood stream of poisons, toxins, viruses and bacteria if the plasma is saturated with Vitamin C. Fever, toxins and bacteria reduce the level of C. Therefore, Dr. Klenner theorizes, if a high level of C is maintained, all tissues return to normal despite the fever and the bacteria; and because of its action ââ¬Åas a respiratory catalyst, it enables the body to build up adequate resistance to the invader.ââ¬Â
The anaerobic condition in the tissue is relieved. Acidity is decreased and large amounts of Adrenaline disappear. The constriction of the blood vessels ceases and the liver and pancreas can receive the proper nutrients to function. Properly calculated doses of C on a continuing basis will restore the normal physiology of the body.
The adrenals and Vitamin C are interrelated. During an infection Vitamin C is absent from the urine and is decreased or absent in blood, even when moderate amounts are being given intravenously. Vitamin C in the adrenal glands was greatly reduced in animals succumbing to polio. (Dr. Klenner cites the literature of 1934-35 to document this.) Hans Selye knew how the adrenals would show damage with stress. He found that all patients ill with a virus would show petechial hemorrhages (small leaks of blood into the skin) when a tourniquet was applied to increase venous backpressure. Capillary weakness is a sign of low levels of Vitamin C. Sugar in the urine, associated with the petechiæ, disappeared when adequate serum levels of Vitamin C were obtained.
It is known the C regulates the intercellular substance of the capillary wall. The collagen of all fibrous tissue structures is dependent on an adequate level of Vitamin C. Increased capillary fragility is observed in individuals when the blood level of C drops to 1 mg per liter. These weak capillary walls may allow a simple virus to invade the brain (see ââ¬ÅInsidious Virusââ¬Â).
In addition, Vitamin C acts as catalyst in the assimilation of iron.
(Ascorbic acid is a necessary coenzyme in the metabolic oxidation of tyrosine. The latter is necessary to break down protein to a usable amino acid.)
Dr. Klenner states, ââ¬ÅThe importance of Vitamin C as an antibiotic and as the precursor of antibody formation lack scientific appreciation because of its simplicity.ââ¬Â The reluctance of the medical profession to employ it in massive doses like antibiotics has allowed the appearance of allergies as a major problem.
Vitamin C is known to be essential for life. He quotes the studies that show that when Vitamin C is given intravenously to patients with a deficiency, fibroblasts begin to form connective tissue and capillary buds invade blood clots within just a few hours. In a similar time frame when used as an antibiotic, fever falls and the white count climbs.
Dr. Klenner points out that the standard treatment of colds was based on the alkalinizing effect of forcing juices down the patientââ¬â¢s throat. Highly alkaline urine has less Vitamin C. The Vitamin C would be thus retained in the tissues helping to guard against the viruses and bacteria. When Vitamin C levels drop, glycogen in the liver is converted to glucose: a response to stress.
Dr. Klenner is convinced that C will work in any problem but the negative results reported are only because an insufficient amount was used. A tragic error in judgment has been made by the National Academy of Science and the National Research Council: the minimum daily requirement for C. All of us need more; some need a lot more.