I would have to fall on the "don't bother" side of the ol' antidepressant debate.
I was on Effexor for 2.5 years and while it did help, in retrospect, I would say that this benefit was not worth (i) the withdrawals from the drug, (ii) the high cost (for the short period when I was not covered by insurance), or (iii) unfortunately, the side effects-- my main complaint being that my libido was running at 65% during that time.
After I discontinued using it, I may have been a little more anxious in certain times, but I could control it now that I knew it was predominantly an issue of neurochemistry. Also, you don't realize what your libido is to you until you lose it and get it back. I would say that ones sex drive is probably a large part of their passion for life. I never would have said that 3 years ago, but its an amazing revelation (and you appreciate it more too).
Notwithstanding the foregoing, if you are clinically depressed or have been diagnosed with some type of behavioral disorder which is significantly affecting your life, try a few different ones (under a psych.'s guidance, of course). I have heard miracle stories as well.
But never forget--and don't let the FDA and the pharmaceutical industries fool you....these drugs are ADDICTING.
OK...before I get a lot of flames from people who do not agree...you must realize that about ten years ago when the term "addicting" was really only used to describe drugs which could cause a physical dependence in one. We had two terms originally that were used to describe this type of an effect from certain drugs: physical dependence and/or psychological dependence.
Then we ran into crack cocaine (and later crystal meth). Some individuals who used these drugs regularly over time became VERY psychologically dependent to them. But this was not "addicting" like heroin or cigarettes were. THe DEA was stuck saying "psychologically dependent", and I guess, if they couldn't say that cocaine was "addicting" and then compare it to heroin, well, I guess they just weren't having any fun.
So sooner or later they just convinced the AMA to change the whole definition.
I really do not understand what all the different words mean now, except I can tell you that Effexor, Paxil, Zoloft, and others all cause a real physical dependence. Although you do not have the cravings associated with psychological dependencies, you still will feel very ill for days if you stop cold turkey (a word you will never here the pharm co.s use when describing these drugs) and do not titrate off slowly. These drugs have withdrawals just like opiates (heroin, morphine, etc.). In some instances they may be very similar such as nausea, headaches, dizziness, clammy skin, etc., but you won't really feel like you would give two fingers for another pill because there is no association psychologically to the drug.
Lastly, I really feel like all these drugs do is anesthetsize you. They all boost serotonin (other than Wellbutrin which I do endorse for its lack of side effects and its focus on dopamine receptors as opposed to serotonin receptors) and basically make you emotionally "foggy". In other words, You won't get really upset anymore if say Oprah is a rerun today, but on the other hand, the little things in life that might have made you happy or excited (like the change in seasons or say, your libido) don't really do it anymore. For some people losing the mental anguish at the expense of these things is a sound trade-off. But for others who may just want a little fun or a better disposition....I'd recommend exercise, a hobby, or a trip to amsterdam.
Parker