Oanda is open Saturday and Sunday (iirc they are only closed for maintenance friday evening EST), so you can hedge there (if you are in otc fx options or 6E, etc.), in theory. 10 pip spread (maybe a little more) on Eur/Usd on sat thru sunday morning, goes down to 5 pips by 1-2pm EST Sunday (NZ and australia online), and ofc everywhere else is running by 5pm. Eat a 10 pip spread to hedge a possible 100+pip move might be okay for some. Never looked into it myself but it probably came in handy on those fall weekends in '08 when no one was sure what would happen by Monday. If it's a real macro/geopolitical event tho, would imagine those spreads, spread. I believe there is or was another fx broker open on the weekends, can't recall now though.