So, at first you should be in a place where algos have a disadvantage because it's a suboptimal environment for them.
Your example of complex news not coded to be machine readable would be one. (#3)
I think there is another example of predictable disadvantage to algos which relates to #6.
They are weak at complex/fuzzy/intuitive work and strong at speed/calculation work.
Therefore (I assume) strategies are going to coalesce around:
A) pure arb/stat arb
B) automated news dissemination
C) microstructre analysis in the product / correlated markets - next tick prediction stuff
D) momentum ignition / sweeping / flipping / spoofing / type strategies
E) market making
Which of these algos could be weak vs a manual trader? I'd go for market making.
Restrictions are maximum position size / inventory permitted by the risk profile, policy to exit positions by the close as you mentioned, limited ability to avoid adverse selection.
One would assume that market making algos will bias their quotes according to inventory, and in some conditions withdraw from quoting on one side of the market when risk limits are reached. In dire cases crossing the market to liquidate positions. And there will be several of these in competition but doing similar things based off similar inputs.
In some circumstances, an intuitive manual trader could identify condition where type E is longer or shorter than desired, A&B (speed) are not relevant, where C would operate as usual, and if D is present it actually helps the trade. In other words, if the manual trader was good at intuiting when enough market participants would cross the market, causing an imbalance and further similar trades, forcing type E to withdraw/bias quotes/cross the market to exit while this new flow continues, then this would be one of the best places for a manual trader at speed/fee disadvantage to trade.
It occurs this knowledge would also be very useful in designing a momentum ignition strategy. If one were able to consistently and accurately read the liquidity of the product and under what specific conditions to pay to sweep the book.
This strategy would be almost an inverse of #1, trading far less frequently, but with an expectancy per roundtrip an order of magnitude larger than your example for #1. You're getting paid for being better informed about future order flow than automated market makers. Not easy or I wouldn't write this here.