True it is a huge market but it is not a traded market. Most of those securities are privately placed with hedge funds, pension plans or large investment banks. You are not going to get retail traders working MBS trades, those move in millions to institutional houses. as for Tbills et al, again, not much discussion can be generated because no one is trading them here. I dont see any commercial paper trading hands at the retail level.
Thos are really outside the scope of this forum.