If I'm simply long calls or puts, I've backtested that if you see it decline 50%, you're almost always wishing upon a star that it will come back. 30% is another good waypoint. You really shouldn't be going down much if it's going to be good. 10% is no big deal as it comes with spreads and maybe 1-2% slippage from your equivalent stock entry.
For stocks, a 2% starts to concern me a little, but I wouldn't leave until 5%. I position trade for a minimum 10% gain and trade options only for doubles btw, I'm not a daytrader.
On an account, 20% is a good area to pack it in and re-up. It takes so much good work to rebuild from drawdowns of more than that. It's not worth it even if it that position comes back. A couple of those and you need to achieve a double to get your account flat.
Wilt