Quote from braincell:
It does get killed in a trend. MM HFTs prefer slow moving instruments with large ticks.
Well it doesn't get killed completely. They still get a bid/ask range to stick around for a few seconds, but how long they stay at it depends on their algos and how much market orders they are willing to sustain before bailing out due to loss of symmetry. Those are HFT strategies for market making, they aren't all exactly the same. Many involve arbitrage in the same go, allowing them to keep a bid/ask position for longer even if the symmetry is lost because they can assume it will restore itself due to the arb info they posses. There are many variants but the logic is about the same.
Even with short trends, the spread stays steady long enough for them to make fractions of a cent at a time, and this adds up over time.
For instruments like AAPL where the tick is rather small (the spread can be a dozen ticks) it gets harder for them also. This is because non-hft directional traders can afford to tighten the spread by posting a buy limit above the bid. If the spread is too tight, the HFT won't make money because they still have to pay fractional commissions. That's why they like stocks with higher volume, less trending, and lower absolute price (ie in the 20s).