Quote from austinp:
ES is same as ZB these days: limited range, heavy chop inside the range.
When markets are trending or normal up/down intraday swings, ES offers plenty of potential. When the range is 6pts intraday, the chop is killer.
NQ has a lot less of that, due to 1/10th liquidity of ES. Big-money bot scalpers cannot play the same games in ER or NQ that they do in ES (with YM moving in sympathy to ES) due to limited liquidity.

Quote from fearless9:
Many here swear by the NQ over ES.
I would be interested to read what is their reasoning and what are the advantages.
Since I have never traded the NQ, I hold no opinion.