They already had enough anecdotal evidences and that is why they started the double blind.Agreed
Condition of patient mortality percentage rate got enough back history to estimate that well, start of trial.
Then if only 30% of the 50% die then it works for people at that stage go with it.
Then apply logic to to 60, 70,80,90% groups.
No need for double blind not looking for a 1% improvement, we know the out come, no point 50% of the group false hope and sugar tablets.
Few hours with an excel sheet easy.
Role on the stats
I am quite sure the evidence is not overwhelming or they would have stopped the trials. The question is cure rate, who can be helped and it is worthwhile to approve?