Verticals for most part..
One simple example with a vertical would be to assume that it is approximately like pricing a binary (the replicating portfolio for a binary option is an infinitely tight vertical).
Say you want to price the 100 / 110 call spread (numbers made up):
Call Spread = (BS Value (100, ATM vol) - BS Value (110, ATM vol)) + Vega (105 strike) * (Skew Slope).
So if the skew were negatively sloped, and the 100 call traded 1 IV point over the 110, then the "Skew Slope" factor to multiply the midpoint vega by would be 1%.