This may be way over my league. When I explored trading strategy in 2015, I ran thousands of optimizations to narrow down to a few strategies (both trend following and mean reversion) that has worked 3 years running. I figure if it worked every year, then something must be right. Those strategies went live in 2015 with mixed result so I shut them down. I still run forward tests occassionally and I found out that 2016 and 2017 are both losers. I imagine those funds got funding because their strategies were right for some length of time. I would be confident too if my strategies worked that well for so long. But something in the market chemistry just change, so much so that even HFT is waning.
Perhaps the only thing that doesn't change is the fact that market always changes.
You mentioned you had both trend following and mean reversion strategies. Both were losers in 2016 and 2017? I would expect mean reversion to be inversely correlated with trend-following since they sound like polar opposites in strategy. I am surprised both were losers for 2 consecutive years.