If leaving your job carries a high risk that you will struggle to get it back or something similar, then I would advise against.
Couple of reasons, I dont think anything less than $400k in the piggy bank is safe to live on.
Living expenses are dramatically different depending on where you live and what your lifestyle is. You could be a hippie who wears flip-flops and grows his own vegetables in some 2nd world country or someone who wouldn't ever travel in economy living in New York or Singapore. 400k is a good number but 120-150k is plenty for most.
