The French are fleeing Paris in massive numbers before the next lockdown.

CFR is best estimated using closed cases

Of course.... and as noted by an entire section in Worldmeter on CFR calcualtions.... until a pandemic is over then the precise CFR with closed cases will not be known. There are methods of providing the most accurate CFR while a pandemic is ongoing -- including the reality that deaths are offset in time T several weeks from the reported cases.

Worldmeter discusses some of this here - https://www.worldometers.info/coronavirus/coronavirus-death-rate/#correct

Their text is below

The correct formula, therefore, would appear to be:

CFR = deaths at day.x / cases at day.x-{T}
(where T = average time period from case confirmation to death)

This would constitute a fair attempt to use values for cases and deaths belonging to the same group of patients.

One issue can be that of determining whether there is enough data to estimate T with any precision, but it is certainly not T = 0 (what is implicitly used when applying the formula current deaths / current cases to determine CFR during an ongoing outbreak).

Let's take, for example, the data at the end of February 8, 2020: 813 deaths (cumulative total) and 37,552 cases (cumulative total) worldwide.

If we use the formula (deaths / cases) we get:

813 / 37,552 = 2.2% CFR (flawed formula).

With a conservative estimate of T = 7 days as the average period from case confirmation to death, we would correct the above formula by using February 1 cumulative cases, which were 14,381, in the denominator:

Feb. 8 deaths / Feb. 1 cases = 813 / 14,381 = 5.7% CFR (correct formula, and estimating T=7).

T could be estimated by simply looking at the value of (current total deaths + current total recovered) and pair it with a case total in the past that has the same value. For the above formula, the matching dates would be January 26/27, providing an estimate for T of 12 to 13 days. This method of estimating T uses the same logic of the following method, and therefore will yield the same result.

An alternative method, which has the advantage of not having to estimate a variable, and that is mentioned in the American Journal of Epidemiology study cited previously as a simple method that nevertheless could work reasonably well if the hazards of death and recovery at any time t measured from admission to the hospital, conditional on an event occurring at time t, are proportional, would be to use the formula:
 
Of course.... and as noted by an entire section in Worldmeter on CFR calcualtions.... until a pandemic is over then the precise CFR with closed cases will not be known. There are methods of providing the most accurate CFR while a pandemic is ongoing -- including the reality that deaths are offset in time T several weeks from the reported cases.

Worldmeter discusses some of this here - https://www.worldometers.info/coronavirus/coronavirus-death-rate/#correct

Their text is below

The correct formula, therefore, would appear to be:

CFR = deaths at day.x / cases at day.x-{T}
(where T = average time period from case confirmation to death)

This would constitute a fair attempt to use values for cases and deaths belonging to the same group of patients.

One issue can be that of determining whether there is enough data to estimate T with any precision, but it is certainly not T = 0 (what is implicitly used when applying the formula current deaths / current cases to determine CFR during an ongoing outbreak).

Let's take, for example, the data at the end of February 8, 2020: 813 deaths (cumulative total) and 37,552 cases (cumulative total) worldwide.

If we use the formula (deaths / cases) we get:

813 / 37,552 = 2.2% CFR (flawed formula).

With a conservative estimate of T = 7 days as the average period from case confirmation to death, we would correct the above formula by using February 1 cumulative cases, which were 14,381, in the denominator:

Feb. 8 deaths / Feb. 1 cases = 813 / 14,381 = 5.7% CFR (correct formula, and estimating T=7).

T could be estimated by simply looking at the value of (current total deaths + current total recovered) and pair it with a case total in the past that has the same value. For the above formula, the matching dates would be January 26/27, providing an estimate for T of 12 to 13 days. This method of estimating T uses the same logic of the following method, and therefore will yield the same result.

An alternative method, which has the advantage of not having to estimate a variable, and that is mentioned in the American Journal of Epidemiology study cited previously as a simple method that nevertheless could work reasonably well if the hazards of death and recovery at any time t measured from admission to the hospital, conditional on an event occurring at time t, are proportional, would be to use the formula:
??
upload_2020-11-1_12-32-25.png
 

Yes... and Worldmeter covers all of this in their detailed discussion. Since cases are normally only closes 8 weeks or more after they are reported... while in the midst of a pandemic it makes sense to use reported cases to get a more accurate and current CFR figure --- the real question is the time delay T for deaths (if used) to get a accurate numerator in the equation.

Note that Worldmeter does not call this 4% figure the CFR --- it is the percentage of deaths divided by closed cases.
 
Back
Top