Separate Drives or partitioning larger drives to separate Data from OP System/program files is common. Many take it one step further and have separate drives for each data type, documents, photos, Videos etc...
Operating System and Program files on your "C" Drive with Data files on your "D" drive is a common configuration.
Windows 7 uses Library's. Moving your primary libraries over the D Drive is relatively straightforward. This makes storing data on your "D" drive intuitive.
Here is a good guide on configuring Windows 7, it explains how to move library's
http://www.tweakhound.com/windows7/tweaking/index.html
I suggest moving your primary Library's "My Document", "My Pictures". "My Videos", "My Downloads" over to your "D" Drive.
If you use Google Drive or DropBox, install their respective folders on the "D" Drive as well..
I leave IB-TWS on the "C" drive
I leave Button Trader on the "C" drive
I leave Multi Charts on the "C" drive
I leave Tradestation on the "C" drive
However, I do create folders for Desktops and Workspaces in My documents on the "D" Drive for Tradestation and Multi-charts.
Read the guide carefully before you change anything. Not everything needs be tweaked... Customizing start menus, task bars and moving library's, you will be fine.
If this system is Windows 8, not sure on configuration. As I pulled Win8 of my systems within hours of installing it. In any event, here is a Win8 tweak guide for reference.
http://www.tweakhound.com/tag/windows-8/
SSD configuration is basically the same as a conventional drive, just keep in mind that you do not want to disk defrag SSD's.