....
Eligible participants were allocated at a 1:1 ratio to receive orally (or via nasogastric tube in case of orotracheal intubation) either:
a) high doseCQ (600mg CQ (4x150mg tablets, twice daily for 10 days, total dose 12g);
or b) low dose CQ (450mg CQ (3x150mg tablets + 1 placebo) twice daily on Day 0, 3x150mg tablets +1 placebo tablet followed by 4 placebo tablets from D1 to D4, and then 4 placebo tablets twice daily from D5-D9, total dose 2.7g).
Hell of a trial. So go from a high success rate of 2.7 grams of the thing, to FOUR TIMES the successful group, and people start dying.
Way to go clinical trial doctors? Why not simply up the working dose by half, so maybe only 5-6 grams for the second arm? Or maybe, *GOD FORBID*, try a third group with 1 gram?
Shit, why didn't they just up the second group to 454 grams, and shoot them up with a pound of the stuff from the start? In fact, why didn't they just say screw it, let's exchange their blood for HCQ, see how they fare?
Total failure of a trial. Ridiculous bullshit. And these people get paid hundreds of thousands of dollars per year.
Eligible participants were allocated at a 1:1 ratio to receive orally (or via nasogastric tube in case of orotracheal intubation) either:
a) high doseCQ (600mg CQ (4x150mg tablets, twice daily for 10 days, total dose 12g);
or b) low dose CQ (450mg CQ (3x150mg tablets + 1 placebo) twice daily on Day 0, 3x150mg tablets +1 placebo tablet followed by 4 placebo tablets from D1 to D4, and then 4 placebo tablets twice daily from D5-D9, total dose 2.7g).
Hell of a trial. So go from a high success rate of 2.7 grams of the thing, to FOUR TIMES the successful group, and people start dying.
Way to go clinical trial doctors? Why not simply up the working dose by half, so maybe only 5-6 grams for the second arm? Or maybe, *GOD FORBID*, try a third group with 1 gram?
Shit, why didn't they just up the second group to 454 grams, and shoot them up with a pound of the stuff from the start? In fact, why didn't they just say screw it, let's exchange their blood for HCQ, see how they fare?
Total failure of a trial. Ridiculous bullshit. And these people get paid hundreds of thousands of dollars per year.