In a way the suicide of the of the once great , but not in the best sense of the word, Grand Old Party, is a fitting end. Just one more example of Reaping What One Sows.
The Republican Party's natural constituents, those who can actually vote anyway, are far to few to win elections; the remainder of constituents being only able to vote with dollars rather than ballots. The Party has therefore been forced to open its doors to disparate groups and hold them together by lying. Considering this, I suppose it was inevitable that one or the other of these lunatic fringe groups they invited in would eventually seize control of the party.
Trump will be fighting one or more indictments be 2024, making any campaign of his appear ludicrous to the majority of voters, including those actual Republicans like Romney and Cheney who have been cast off like old shoes. Those who have no moral compass nor any guiding principles other then their own selfish interests, like McConnell, will inevitably go down with the ship.
This is sad, and the Democrats should be alarmed rather than happy. They need a strong opposition party to keep them from the pitfall of unbridled excesses.
The midterm election outcome is quite uncertain because we know not yet whether State Legislatures' attempts to make voting less convenient for minorities will have their intended results. But we can be quite sure that the many court challenges will have had time to wend their way through the Courts by 2024 and that by then the Democrats will have perfected countermeasures. Consequently, it's a fairly safe bet that the 2024 election will see another disastrous loss for those who have now usurped the "Republican" name. After that, there will certainly be a realignment and possibly the birth of an entirely new Party. In the meantime the Wall Street and Corporate America that we have come to know are in the process of being left stripped bare of the protection they have come to take for granted from what is now the extinct Republican Party.
The Republican Party, since at least the Days of McKinley and the Spanish American War, have been the protectors of businesses' interests. The Business World will be uneasy entrusting that role to a bunch of lunatics. McConnell will still be there, most likely, up to 2024, and will still, with his monotone drone, simultaneously mellifluous and maliferous*, control the present day Senators on his side of the isle. He won't, however, be able to control the lunatics who he now must depend on to maintain power. He's left in terrible straits.
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* I considered "insalubrious" here, but that's perhaps going a bit too far.