The hedge fund industry, and quantitative analysis are still very much intact, imo.
As to the former, it is still in the early stages of a typical S type curve of a strongly growing, emerging industry, as it is becoming conventional wisdom among institutional asset managers to use hedge funds to reduce portfolio risk.
As far as the general correlation and quantitative funds, I don't think a sample size of 10 out of almost 10000 is significant per se. As to quantitative funds, the implication that all of these have had severe drawdowns, or outsized drawdowns compared to discretionary funds, seems unlikely. Some quantitative funds, no doubt, were net long volatility, short CDOs, etc, and did very well.
I do think that recent events will lead investors to more closely analyze the source of returns of hedge funds; is it coming from alpha or is it coming predominantly from beta towards extremely risky asset classes, and this is good for the industry going forward. I suspect over time, fees towards exposure to beta will become somewhat "index-ized" or commoditized, leading towards less of a justification for high fees, just as is happening in many "closet-index" long mutual funds that don't demonstrate long term outperformance with equities. I think there will always be a premium for demonstrated alpha, however.