Quote from spindr0:
Before you can determine if there an option strategy to profit from this you have to determine if there's an UL pairs strategy that works.
Forget the "negative" part of the correlation for a moment because that's just a question of direction (long or short).
A good situation for a standard pairs trading strategy (one long, one short) is one where the sum of daily changes (the pair difference) swings back and forth in some range of regularity. You're objective is to trade the spread (expansion or contraction).
For example, take the ideal sine wave. At the peaks, the spread is the widest and that is where or near where you take your position, shorting the overvalued and buying the undervalued. Under/over value may be the wrong word usage. Perhaps extreme value would be more appropriate.
There's no guarantee that when you take a position at what you think is a peak that it will be a peak. The spread difference may widen more and if your concept has legs and you believe in it, you add more. There are times when you just have to carry a position.
Most likely, this spread also jiggles around intraday and if so, that presents an opportunity to shift your intraday bias, adding more to one side or vice versa, getting back to whatever you deem flat to be by EOD. This involves having some idea of what moves the UL's - for ex, interest rates, oil or gold prices, good/bad day for a sector, etc.
If there are any other equities that are correlated similarly, you can take winners off the table and substitute them but that's another story.
Once you determine the tradeability of the pairs, then you can look at option scenarios. I will confess that I've done the above with UL's but have not found a reliable way to do so with options.