Hello,
Say I have an opinion that instrument X is above/below price Y at time Z with probability of say 65%. How could I make a binary bet on this outcome using vanilla instruments on major regulated exchanges, such as CME?
Appreciate any advice!

CVR stands for Contingent Value Right. This CVR will entitle you to receive a one-time potential payment of $9.00 in cash upon Federal Drug Administration (FDA) approval in specified indications of all three of the following milestones:
If the CVR milestones are not all achieved, no payment will be made, and the CVRs will expire.
- ozanimod by December 31, 2020,
- liso-cel (JCAR017) by December 31, 2020, and
- ide-cel (bb2121) by March 31, 2021.
I've looked at this some. And like others have said it's easy to construct a 50/50 R/R with a simple vertical credit or debit spread. Almost seems like a no-brainer: even money bet, with a 65% win rate. You'd own Vegas.
The catch is your time frame. If your underlying move is not near the vert expiry, you are not going to make that much, unless of course it zooms past your strikes. And to hold it to near expiration invites a reversal. If my systems indicate a move I just grab a near money long option. Limited loss, "unlimited" gain, and no short option hassles.![]()