Quote from snackly:
Well yes, you need to account for what affect you'll have on the market, however there are heuristics that one can use to approximate that. And of course that impact largely depends on the size of the order, the liquidity of the market, the depth of the market (presuming you're not in a multi-contributor market), and the exchange order priority algorithms, etc.
But thanks for pointing this out, it's very valid. That said, don't think that people don't backtest tick strategies. Clearly not everyone is crazy enough to just trade tick strategies without testing it against some set of assumptions.