NO! Why the hell you have your Remington 870 loaded with slugs? At that point you are just doing a Tremors II deal...
Like Calhoun said, an AR-15 is too much for home protection. A nice fat slow .45ACP or scatterload will do well in home defense. You don't need penetration!
Even the Mythbusters learned that when they shot a cannonball out of some homemade thing, and it went through someone's home a mile away, and they had to apologize on air months later (Nobody was hurt in that incident, thankfully.)
