First anyone referring to an mRNA vaccine as gene therapy is pushing complete antivaxxer nonsense. mRNA vaccines do not alter genes, they are not "gene therapy" or do any "gene replacement" --- all of these talking points are nonsense being pushed by COVID-deniers and antivaxxers.
It should be noted that other mRNA vaccines for cancer and other diseases have been developed, placed in trials, and studied for years. Any long-term consequences of mRNA vaccines based on the technology are well known by now -- and there are no long term significant consequences related to a vaccine being based on mRNA technology other than other technology.
Let's get to the facts of the vaccines and long term effects.. We will start with quoting a section of the following article...
Covid-19 vaccine myths: These reasons for not getting a shot don't hold up. In fact, they'll set the US back
https://www.cnn.com/2021/04/28/health/covid-vaccine-myths-debunked/index.html
'We don't know what the long-term side effects are'
Any adverse side effects from vaccines almost always "show up within the first two weeks, and certainly by the first two months," said Dr. Ashish Jha, dean of the Brown University School of Public Health.
That's why he and many other health experts asked the US Food and Drug Administration to wait at least two months after trial participants had been inoculated before considering whether to give emergency authorization to Covid-19 vaccines.
"If there were going to (be) problems ... they would become apparent within two months of people getting vaccinated," he said. "That's what the FDA waited for."
The most serious vaccine side effects in history have all been caught within six weeks, said Dr. Paul Offit, director of the Vaccine Education Center at the Children's Hospital in Philadelphia and a member of the FDA's Vaccines and Related Biological Products Advisory Committee.
"I would say, please tell me what vaccine has ever been shown to cause a long-term side effect that was not picked up in the first two months," said Offit, a co-creator of the rotavirus vaccine who has studied vaccinology for more than four decades.
"The smallpox vaccine could cause inflammation of the heart muscle. The oral polio vaccine was a rare cause of polio -- it occurred in roughly 1 in 2.4 million doses. ... The yellow fever vaccine is a rare cause of ... yellow fever. All those occurred within six weeks of getting a dose," he said.
There may be very rare side effects that aren't immediately found in clinical trials. But that's due to the extreme rarity of those side effects -- "not because it's a long-term problem," Offit said.
"Sometimes you're not going to pick it up initially because it's extremely rare, so you aren't going to pick up a one-in-a-million risk in a trial of 44,000 people," he said.
Pfizer/BioNTech and Johnson & Johnson had about 44,000 participants in each of their trials. Half the volunteers got vaccinated, and the other half got placebos.
The Moderna trial had about 30,000 participants, with half receiving vaccines and half receiving placebos.
And because
coronavirus is highly contagious -- killing
more than half a million Americans and leaving
many survivors with long-term complications -- you're much better off getting the vaccine.