Alright the one thing i don't like about the Evelo upgrade is it comes after a a down $1 8% day yesterday which could of prompted this save upgrade.... If it was down for no no good reason i would have done the same thing...
Evelo Bio rises 15% on positive EDP1815 data in atopic dermatitis
Dec. 09, 2020 8:00 AM ETEvelo Biosciences, Inc. (EVLO)
Evelo Bio rises 15% on positive EDP1815 data in atopic dermatitis
Dec. 09, 2020 8:00 AM ETEvelo Biosciences, Inc. (EVLO)
- Evelo Biosciences(NASDAQ:EVLO) jumps 15% premarket on positivetopline datafrom its Phase 1b clinical trial of EDP1815 in 23 evaluable subjects with mild to moderate atopic dermatitis.
- The primary endpoint was safety and tolerability. EDP1815 was well tolerated with no serious adverse events.
- Clinical differences between EDP1815 and placebo were statistically significant at day 56 in both the percentage change in EASI (62% difference, p=0.034) and in IGA*BSA (71% difference, p=0.019).
- Improvements in these measures were observed as early as day 14.
- At day 56, 10/16 patients in the active group showed improvements in EASI score, compared to 0/7 of patients in the placebo group.
- These results provide further evidence that modulating SINTAX can drive significant clinical benefit without the need for systemic exposure.
- The company looks forward to sharing the complete dataset from this Phase 1b trial in early 2021 and advancing EDP1815 into later-stage trials.