I do use QT, but not with TWS (I use QT for stocks with Ameritrade, and IB with Ensign + my own homegrown software).
Never seen anything like this before using IB with my own software.
The only thing I can think of that may have caused this, is that I lost my data connection during the early, early morning hours, but it reconnected by itself, and everything appeared ok when I quickly looked at it during the pre-market.
But, after the regular session began, that's when I started noticing tons of negative volume ticks (they would appear BLANK in the IB screen where Last volume usually is seen), plus prints going off above and below the offer and the bid as displayed on TWS.
Like I said, never saw anything like this before. This continued for a couple of hours until I finally decided to close TWS and restart my software. Then things went back to "normal"
What was even weirder was the fact that I was getting a much more granular feed than I have ever seen on IB TWS....made me think they had changed to a true tick by tick T&S.....
Very, very strange.....