How much does an individual trade affect a stocks price?

A very hypothetical question I'm sure, but All things considered (Volume, Liquidity, etc) how much does an individual transaction affect stock price?

A specific example: Do you think a single Market buy of $100kof MSFT will have a tangible effect on the stocks price under any circumstances? What about $200k @Market?

Or what about a tracking stock like QQQ or DIA.. any personal experiences?
 
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