"Results: For every 10-g/d increase in saturated fat intake, IMT was 0.03 mm higher (P = 0.01) after multivariate adjustment. A 1-g/d higher intake of trans fat was associated with a 0.03-mm higher IMT (P = 0.02) after multivariate adjustment. The ratio of polyunsaturated to saturated fat (P:S) was inversely associated with IMT after multivariate adjustment (change in IMT: â0.06 mm; P < 0.01). Saturated and trans fat intakes were independently associated with IMT thickness (change in IMT: 0.03 mm; P < 0.01 and 0.02, respectively; P for interaction = 0.01). Polyunsaturated, monounsaturated, cholesterol, and total fat intakes were unrelated to IMT. The relation between saturated fat intake and IMT strengthened (β = 0.0066, P < 0.001) in persons who never or rarely consumed alcohol as compared with moderate or heavy drinkers (β = 0.0001, P = 0.79, P for interaction = 0.01)."
Interrelation of saturated fat, trans fat, alcohol intake, and subclinical atherosclerosis1,2,3
Anwar T Merchant, Linda E Kelemen, Lawrence de Koning, Eva Lonn, Vlad Vuksan, Ruby Jacobs, Bonnie Davis, Koon K Teo, Salim Yusuf, Sonia S Anand for the SHARE and SHARE-AP investigators
1 From the Population Health Research Institute, Hamilton, Canada (ATM, LdK, EL, RJ, BD, KKT, SY, and SSA); McMaster University, Hamilton, Canada (ATM, LdK, KKT, SY, and SSA); Hamilton Health Sciences, Hamilton, Canada (EL, KKT, SY, and SSA); the Alberta Cancer Board, Calgary, Canada (LEK); the University of Toronto, Toronto, Canada (VV); and Six Nations Health Services, Ohsweken, Canada (RJ and BD)
http://www.ajcn.org/cgi/content/abstract/87/1/168
Dietary saturated and trans fat increase LDL and total cholesterol. For you to make such a bold statement of no connection between cholesterol and heart disease and that it's all a conspiracy by medical community and pharms is ludicrous and reckless reasoning.
:eek: