tradestation, Amibroker and ninjatrader. I like my Tos though, try not to over trade in a year. As far as automation goes I use algs for discovery, and validation but as for order placement that's done by hand. Years ago I was running TD Strategy Desk 2006. I backtested for year plus research, then started running real time. back testing showed great results but real time I had a bad run of false positive triggers that would initiated a trade.