I would stay clear of ML for now - but if you insist, you can plug into Azure very easily from Excel 365.
I personally use Excel's Solver.
Nice. Not many appreciate the power of optimization packages. Have you tried any other solvers/optimizers other than Excel's/Frontline's?
I saw a guy from Google's AI the other day who said that ML starts making sense above 10mil data points

Gotcha.
Lol ... well ... I'm sure ... it depends.
(Also, I'm sure there's some bias involved in making such a general statement. I figure ... this guy only works with 10 mil+ data points in his occupation.)
____________
"To a carpenter, everything is a nail."
I would stay clear of ML for now - but if you insist, you can plug into Azure very easily from Excel 365.
I personally use Excel's Solver.