Has anyone managed to negotiate lower fees with IB?

Fair enough. It's $1m at IB but they will charge you $1000 per month that can be netted off against commissions. So if you generate 1000 in commissions, you won't pay anything.

I personally think that you need 5m+ (as you say) to make the best out of it.
Prime brokerage is based on "need", not cost. You need a service your Prime does not offer.
 
I have no idea, but co-location is not a strategy, it is necessity for low latency. Low latency is very expensive from hosting fees to non-display fees. The AUM has to be material and the edge has to require this, It is not uncommon for this to get >$15K to $20K/month if you need NYSE Data all in.
 
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