Quote from Grandluxe:
But you were talking about lungs. Seems that someone dosen't know their science.
i never used the word cancer even though i dont believe 1 study showing no causation:
Does the regular smoking of marijuana cause lung cancer or in any way permanently injure the lungs?
Richard Beasley, MBChB, DM, FRACP, DSc, Director of the Medical Research Institute of New Zealand, in a Jan. 29, 2008 interview with Reuters explaining the results of his Feb. 2008 study "Cannabis Use and Risk of Lung Cancer: a Caseâcontrol Study" in the European Respiratory Journal:
"Cannabis smokers end up with five times more carbon monoxide in their bloodstream (than tobacco smokers)...
In the near future we may see an 'epidemic' of lung cancers connected with this new carcinogen. And the future risk probably applies to many other countries, where increasing use of cannabis among young adults and adolescents is becoming a major public health problem."
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Donald P. Tashkin, MD, Director of the Pulmonary Function Laboratories at the University of California, Los Angeles, wrote in his Mar. 1997 article for the Center for Substance Abuse Prevention titled "Effects of Marijuana on the Lung and Its Immune Defenses":
"Analysis of the smoke contents of marijuana and tobacco reveals much the same gas phase constituents, including chemicals known to be toxic to respiratory tissue...
With regard to the carcinogenic potential of marijuana, it is noteworthy that the tar phase of marijuana smoke contains many of the same carcinogenic compounds contained in tobacco smoke, including polycyclic aromatic hydrocarbons, such as benz[a]pyrene, which was recently identified as a key factor promoting human lung cancer...
Bronchial immunohistology revealed overexpression of genetic markers of lung tumor progression in smokers of marijuana.
Preliminary findings suggest that marijuana smoke activates cytochrome P4501A1, the enzyme that converts polycyclic hydrocarbons, such as benz[a]pyrene, into active carcinogens."
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The American College of Physicians (ACP) wrote in its Feb. 15, 2008 position paper "Supporting Research into the Therapeutic Role of Marijuana":
"The chronic effects of smoked marijuana are of much greater concern, as its gas and tar phases contain many of the same compounds as tobacco smoke. Chronic use of smoked marijuana is associated with increased risk of cancer, lung damage, bacterial pneumonia, and poor pregnancy outcomes."
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Jeanette M. Tetrault, MD, Clinical Epidemiologist at the Connecticut Department of Veterans Affairs, et al., stated in the article "Effects of Marijuana Smoking on Pulmonary Function and Respiratory Complications: A Systematic Review," published in the Feb. 12, 2007 issue of Archives of Internal Medicine:
"Conclusions: Short-term exposure to marijuana is associated with bronchodilation [opening of the air passages]. Physiologic data were inconclusive regarding an association between long-term marijuana smoking and airflow obstruction measures. Long-term marijuana smoking is associated with increased respiratory symptoms suggestive of obstructive lung disease."
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Charles Ksir, PhD, Professor Emeritus of Psychopharmacology and Drug Policy at the University of Wyoming, and Oakley Ray, PhD, Emeritus Professor of Psychology and Pharmacology at Vanderbilt University, wrote in their 2004 textbook Drugs, Society and Human Behavior:
"Experiments have shown that chronic, daily smoking of marijuana impairs air flow in and out of the lungs. It is hard to tell yet whether years of such an effect results in permanent, major obstructive lung disease in the same way that smoking tobacco cigarettes does.
Also, there is no direct evidence linking marijuana smoking to lung cancer in humans. Remember that it took many years of cigarette smoking by millions of Americans before the links between tobacco and lung cancer and other lung diseases were shown...
Everyone suspects that marijuana smoking will eventually be shown to cause cancer, but how much of a problem this will be, compared with tobacco, is hard to say."
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Ted Sarafian, PhD, Associate Research Scientist of Pulmonary and Critical Care Medicine in the Department of Medicine at the University of California at Los Angeles (UCLA) David Geffen School of Medicine, et al., wrote in their June 1999 study "Oxidative Stress Produced by Marijuana Smoke" in the American Journal of Respiratory Cell and Molecular Biology:
"Marijuana (MJ) smoking produces inflammation, edema, and cell injury in the tracheobronchial mucosa of smokers and may be a risk factor for lung cancer...
We conclude that MJ [marijuana] smoke containing Delta-9-THC is a potent source of cellular oxidative stress that could contribute significantly to cell injury and dysfunction in the lungs of smokers."