GBA Presents: House of Gummy-!

I DON'T CARE THAT MONEY FLOW AINT GREAT CRSPR IS ONE OF THE BEST IDEAS NOW.

As of late last year, CRISPR and Vertex started submitting exa-cel, their blood disorders candidate, to regulatory agencies in the U.S., the U.K., and Europe. The FDA aims to issue a decision on exa-cel for sickle cell disease in December and on exa-cel for beta thalassemia in March.


Data have been strong for both indications, so there's reason to be optimistic about exa-cel's future. For example, 94% of patients in the sickle cell trial remained free of pain crises for at least one full year. In the beta thalassemia trial, more than 88% didn't require blood transfusions for at least 12 straight months.


CRSP.png

NASDAQ: CRSP
CRISPR Therapeutics
Today's Change
(1.39%) $0.61
Current Price
$44.45
CRSP
Key Data Points
Market Cap
$3B
Day's Range
$43.67 - $45.55

Potential for blockbuster revenue
Exa-cel could generate $1.7 billion in revenue in 2028, according to Evaluate Pharma, which puts it in blockbuster territory. Of course, CRISPR shares profit with Vertex, and Vertex will take the lion's share -- 60% -- since it also is making a bigger investment in the program's costs. But the potential product still represents a significant amount of revenue for CRISPR.

It's also important to note this isn't CRISPR's only near-term opportunity. The company is studying an immuno-oncology candidate in a trial that could support a regulatory submission. If all goes smoothly, this represents another potential product within the next few years.

Meanwhile, CRISPR is also generating revenue by licensing its gene-editing technology to others. This spring, Vertex bought access to the platform for use in one of its other programs, one targeting type 1 diabetes.




UPDATE- $48--------$52


Crispr Therapeutics call volume above normal and directionally bullish » 13:45 CRSP
 
ADD->Light & Wonder, Inc. (LNW)
NasdaqGS - NasdaqGS Real Time Price.
73.01-0.96(-1.29%)
As of 10:37AM EDT.




GBA SELL---> (LNW) $73------->$85

I get jumpy when stocks move $10./ This is not a good way to build real value.
If I had a large position I would hold. But it's just a few hundred so let's raise
some cash and find something else to buy like PERI.


85.99+7.92(+10.14%)<-------------:thumbsup:
As of 02:12PM EST.
 
GBA SELL---> (LNW) $73------->$85

I get jumpy when stocks move $10./ This is not a good way to build real value.
If I had a large position I would hold. But it's just a few hundred so let's raise
some cash and find something else to buy like PERI.


85.99+7.92(+10.14%)<-------------:thumbsup:
As of 02:12PM EST.
That was a good one...
 

Bearish money manager throws in the towel and buys stocks. Here's what changed his mind on the market.

Bearish money manager throws in the towel and buys stocks. Here's what changed his mind on the market.




  • A self-described "reluctant bear" has thrown in the towel and bought stocks in recent weeks.

  • Money manager Sebastien Page of T. Rowe Price said a surprisingly strong economy should lift stocks higher.

  • Here's why Page changed his view on the stock market and started buying equities again.
A self-described "reluctant bear" has thrown in the towel and started to buy stocks in recent weeks as the US economy continues to surprise to the upside.

Asset manager Sebastien Page of T. Rowe Price told CNBC on Thursday that he waited for a correction in stock prices to add exposure to equities, and the late-October pullback served as an opportune entry point to buy more stocks.

"We bought stocks. We closed our underweight [in stocks]," he said, adding that he purchased $3 billion worth of stocks in recent days and is now overweight small- and mid-cap stocks.

"Growth has been surprising on the upside significantly," Page said, highlighting the economy's continued resilience, with US GDP growing at a 4.9% clip in the third quarter."I think [a] soft landing [in the economy] is the base case."

The top three reasons why Page is not panicking when it comes to investing in the stock market, aside from the continued upside surprises in economic growth, is because of a surge in money market fund assets that hit record highs of $5.70 trillion last week.

That money could serve as fuel for the next stock market rally if yields fall and investors reconsider their cash allocations.

"There are $6 trillion dollars in money market funds right now. That is $2 trillion more than before the pandemic. And that is the big question. Will it move into markets? I don't think that's fully happened yet," Page said.

Additionally, he believes that 5% interest rates were the "old normal" and aren't at a restrictive enough level today that they should limit further gains in stock prices.

Despite his increasingly bullish view, Page said that relative to bonds, stocks still appear expensive.

"The market is reasonably valued, but compared to bonds, stocks are more expensive than they were before the sell-off of 2022. The equity risk premium is most compressed it's been in 20 years... Cash yields are higher than earnings yields on stocks," Page explained.

Sticky inflation also represents a risk to stocks,according to Page, which explains why he hasn't yet gone all in on stocks relative to bonds.

"Now's not the time to be overweight stocks by 10% to 20%, but now is not the time to panic and go all the way to cash either," he said. "In the long run, stocks pay off."

For Page to become a "convinced bull" and go from a neutral weighting towards stocks to an overweight weighting, he wants to see a sharp climax in selling.

"I'd love to see capitulation in the market. I'd like to see the VIX at 30. I'd like to see a panic, and that would be a great opportunity to actually overweight stock if the fundamentals are still good," Page said.

With the VIX currently at just below 15, there's no sign of any capitulation in the stock market yet.











 
Van there was a front page story in the NYT business about when banks close down accounts without asking. This is what happened to me and I freaked out.

Case after case is listed and they all still got stymied and rejected even when they had pretty good excuses.

How did I win.? I sent a letter straight to Mr Dimon. I knew he probably wouldn't see it but I tore into him the way my grandmother would of if she was alive.. all those years she was at Manny Hanny and then Chase her whole life I laid that all out The Private Banking everything and then my mom her whole life, the Retail Lease all drawn up w/ Chase... an then me--all my life w/ Chase I went heavy legacy rout and won.
 
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