Gates Foundation Teams Up With Vaccine Maker to Produce $3 Covid-19 Shots

[vanv0029]

The trials are event driven. After a certain number of people get
Covid-19 the study will be unblinded and the number of infected
who received vaccines versus placebo will be counted. The
vaccines use technology used in other vaccines that work
and have been used for years so they are almost certainly
safe. For example the similar technology GSK Shringrix
Shingles vaccine has been given to 11 million people
since it was approved in 2017 with very few serious
problems.

The halted AZN/Oxford vaccine uses an Adeno virus
where similar side effects have been seen but at a much
lower rate (the vaccine is probably still good because the
vaccinated medical symptoms were just random). All the
vaccines worked on primates so they will probably work at
least to some extent in people.

I think the Warp speed bar for provisional approval
is 50%. The number number of events needed for
approval depends on the size of the trial. PFZ
first readout is 28 days (then next 56). MRNA
first readout is 42 days.

There is a good chance that even 50% effective
vaccines will eliminate Covid-19 once enough people
have been vaccinated because the virus needs humans
as its host.

 

[mlawson71]

I've been hearing stories from within the research fields that there has not been enough representation in the trials by those that Covid-19 tends to kills / make very ill. That is very problematic.

Also, the issue is long term effects from a vaccine or Covid-19 itself. That's something you can not speed up / expedite. If they do that, distrust grows within the community about the safety of the vaccine especially if there's been any political involvement. If the latter happens and there's one case...just one...in which someone has a bad side effect...

Depending upon which poll you decide to believe...50% to 70% Americans say they will not take a vaccine that's released this year 2020 because they believe it will be unsafe due to it being rushed.

In my opinion, anyone (researcher, doctor, nurse, politician) that states that a vaccine is safe...they should be the first one to take it as in the Canaries in the Coal Mine.

The below timeline is for normal trials. In contrast...trials for Covid-19 has been expedited as in its much faster than the info below.

How Long Does a Phase 1 Clinical Trial Take?

The length of a phase 1 study is typically several months.

How Long Does a Phase 2 Clinical Trial Take?

The length of a phase 2 study can span several months to 2 years. This phase involves up to several hundred people, with researchers looking for the effectiveness and safety of the drug over a relatively short period of time.

How Long Does a Phase 3 Clinical Trial Take?

The length of study for phase 3 clinical trials is usually 1 to 4 years. This phase involves 300 to 3,000 patients, with tests designed to determine the drug's longer-term effects.

The Right to Withdraw at Any Time

Participation in a clinical trial is completely voluntary, so you have the right to withdraw from the clinical trial at any time, for any reason.

If you do stop your participation for any reason, you will continue to receive care and advice on your treatment options. You will be asked to return for a final evaluation by the trial doctor, which may include a physical examination and/or laboratory tests.

wrbtrader

Thank you so much for that detailed and informative explanation!

 

[Pekelo]

The Chinese vaccine given to 100K people already has about 5% mild side effects.

That is probably better than the Russian vaccine...

 

[Thor]

Phase III trials are typically several years! I'm pretty sure there are few if any that have been completed in less than 6 months, let alone a month.

When phase 1 and 2 have been rushed thru in months, so will phase 3.
Vaccine before the election, latest before Christmas.

 

[Sig]

When phase 1 and 2 have been rushed thru in months, so will phase 3.
Vaccine before the election, latest before Christmas.

Well Christmas is 3 months away not one. I can see results potentially coming out then at the very earliest, although realistically it's probably Jan. The very phrase "before the election" as opposed to "by early November" indicates political rather than scientific timelines.