Well, I seem to be where I can be, naturally anyway. And although I wouldn't mind getting a bit stronger and adding a couple more pounds of muscle, I'm not complaining. If you've been at it long enough, at a certain point in middle age it becomes about maintenance.
As for your doing more sets to get both stronger and leaner, I fully understand the rationale (and lived by it for years), but the research seems to indicate that most people tend to overshoot on volume beyond what is necessary. I won't pretend to know where the volume sweet spot is. But I can tell you that I'm doing a lot less volume than I used to a few years earlier, and I don't seem to be regressing. And up until the point where I dropped the volume, I was no longer progressing either. So, in retrospect, all that extra volume appears to have been superfluous. I should point out, though, that intensity was always very high, so that part has been a constant.
If you are referring to strength and size, I found that changing my routine every few weeks was the key (at a later age). This included switching from high volume/low weight, low volume/heavy weight, high volume moderate to heavy weight, pyramiding of various styles, adding negatives, super slow reps heavy and/or light, basically an infinite different varieties of approach...whatever kept me from getting bored. Super-setting different groups in ever changing combos over time when possible gave me more efficient workouts. I would use both machines and free weights and utilize various combos of compound and isolation. I still utilize such variety.
At the age of 50 (it might have been a year or so earlier), I began reading Muscle Mag (no longer in circulation), and tried every technique I read about for 2 to 4 weeks at a time (as I described above). I made my biggest and fastest gains between age 50 and 55, including PR's in every muscle group (except quads...knee issues). Between the age of 35 and 50, I never changed my routine...and never got stronger or bigger after the first few months of training.
Again, at least for me, I have little doubt in my mind that variety was the key. (I did so with lots of whey and vitamins...no steroids). I think that variety is more important than the amount of reps and weight utilized, though they are absolutely a factor, too. I found the greatest strength gains came from the slow positive and negative approach...kind of like Mentzer's approach. Those, and centuries are the most brutal workouts for me.
I've just completed a several weeks break after a fairly long period of moderate to heavy weight at high volume, and now will reset to my personal beginning. I didn't really make much gains this last time, but my training was interrupted by transportation problems followed by the gym closing for a time from storm damage, so I don't want to blame the routine or age. I did pick up a few pounds (not presently dieting).
Anyway, after long breaks (over two weeks for me), I start with 1/5th of my max weight per muscle group, and do 48 reps for 1 set, 3 or 4 different exercises per group. After a few weeks I'll add 36 reps for 2 sets at 2/5 max weight, and when I get to 24 reps for 2 to 3 sets at 3/5 of max, I'll begin to once again start mixing things up. I have no plan as to what variety I'll do then, but after a break, and especially at age 56, the high rep/low weight routine to get back in the game seems to "rehab" my joints as I prepare to move into moderate and heavier varieties again.
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Getting old ain't for pussies.