Can you overdose on protein?
Copied from HealthLine.com
Protein is one of the three macronutrients, along with fat and carbohydrate. These are essential for the optimal functioning of the body. However, too much protein — especially with no fat or carbs—can be harmful. This is something to be aware of considering the prevalence of many high-protein diets.
Protein poisoning is when the body takes in too much protein with not enough fat and carbohydrate for a long period of time. Other names for this are “rabbit starvation” or “mal de caribou.” These terms came about to describe only consuming very lean proteins, such as rabbit, without consuming other nutrients. So, although you may be getting enough calories from protein, your body experiences malnourishment from lack of other nutrients, like fat and carbs.
The liver and kidneys play key roles in the metabolism of proteins. When excessive amounts are consumed, it can put the body at risk for increased levels of ammonia, urea, and amino acids in the blood. Although very rare, protein poisoning can be fatal because of these increased levels.
Symptoms of protein poisoning include:
- mood changes
- weakness
- fatigue
- low blood pressure
- hunger and food cravings
- diarrhea
- slow heart rate
What causes it?
To function properly, your body needs:
- protein
- carbohydrates
- fats
- vitamins
- minerals
If there’s too little or too much of any of these, functioning will decline. Even if you’re getting adequate calories from one macronutrient, ensuring there’s balance is important for optimal health.
Excessive protein is defined as greater than 35 percentTrusted Source of total calories you eat, or more than 175 grams of protein for a 2,000-calorie diet. The acceptable macronutrient distribution range (AMDR) is defined as the range that’s associated with reducing the risk for chronic disease while fulfilling the body’s needs of nutrients. The current AMDR according to the Institute of MedicineTrusted Source recommends the following:
- Protein intake: 10 to 35 percent of total calories
- Carbohydrate intake: 45 to 65 percent of total calories
- Fat intake: 20 to 35 percent of total calories
Excessive consumption of macronutrients outside the ADMR may lead to increased risk for chronic disease and insufficient intakes of essential nutrients.
There are exceptions to the AMDR for carbohydrate and fat macronutrients, but not for protein. Diet exceptions include the ketogenic diet, where fat makes up the majority of the diet, or in plant-based diets, where carbohydrates may make up more than 65 percent of the diet. Either of these diets can result in health benefits.
Protein intake exceeding the AMDR or 35 percent of calories doesn’t show these same benefits, and can lead to protein poisoning.