Quote from dmo:
Unfortunately, you're not the only one who knows that company is about to announce the outcome of a clinical trial, so IV will be high.
As for volatility arbitrage - as a retail trader you cannot do volatility arbitrage, but you can do volatility spreads.
But what I've been trying to tell you is that there is no - let me repeat - THERE IS NO ONE-SIZE-FITS-ALL STRATEGY FOR ANYTHING. There is no one thing you can do whenever earnings are about to come out and consistently make money. There is no one thing you can do whenever a clinical trial result is about to be announced and consistently make money.
If there were, that would make it easy to make money trading options. And IT IS NOT EASY TO MAKE MONEY TRADING OPTIONS! Those of us who have been doing this professionally over a period of many years will tell you that it is damned hard work.
I gave you good advice in my last answer. If you want to make money spreading volatility, then stop looking for easy answers and start studying volatility patterns. Maybe you'll see patterns, and maybe you won't.
But if you've been watching the volatility patterns of certain events such as drug-company announcements or earnings over a long period of time, then every now and then you'll see one that is way out of whack. Then instead of getting sucked into whatever excessive excitement or complacency that is driving it out of whack, you'll take the other side. You'll bet against it. You won't make money every time, but you'll have done your homework, you'll be trading with real intelligence, and the odds will be on your side.
There is no shortcut, sorry. If you don't want to believe that, then you are like most retail traders, and there are lots of gurus who will be happy to take your money to sell you their failsafe system.