Look what they do with the bone marrow stem cells. And you can imagine for embryonic stem cells.
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A New Stem Cell Era
Scientists cheer as President Obama ends restrictions on research. What the move means for your future.
(SNIP)
"Talk about the science. What can embryonic stem cells do?
Early on, there was a lot of excitement about the idea of replacement therapyâusing embryonic stem cells to make replacement cells, almost like organ replacement. That is still certainly exciting. But there are two other really exciting things that have happened over the last 10 years. One is creating disease in a dish. The idea is that you create Parkinson's or ALS [amyotrophic lateral sclerosis, or Lou Gehrig's disease] in a dish so that you can watch and understand the process of the disease. Stem cells hold huge promise in that way. Another area that's really cool is creating healthy liver cells or heart cells in a dish so that you can test drugs in the lab before you test them in a person to find out if they're dangerous. Imagine if they'd been able to test Vioxx in a dish before they actually gave it to humans? Or if you could find out that a chemotherapy is toxic before you give it to a cancer patient? The last personalized medicine hope, and we're not there yet, is to create an individual's cells in a dishâcreate Amy's liver or your liver so that you can test a drug in the lab before you give it to me or you. That's a dream, but it is a possibility.
What about critics who say embryonic stem cells are no longer necessary?
We're talking about three different kinds of stem cells: adult stem cells, induced pluripotent cells (iPS) and embryonic stem cells. Embryonic stem cells have the potential to turn into any kind of cell and appear to the have the greatest hope of being differentiated. iPS cells [adult skin cells that have been reprogrammed to an embyronic-stem-cell-like state] are very exciting. But all three forms of research are absolutely necessary to go forward. We have hundreds of diseases in this world that could benefit from one of these three kinds of cells and all deserve to be pursued.
How do you respond to people who are opposed to the destruction of embryos for medical research?
We have to always remember that the largest source of embryonic stem cells are embryos in IVF clinics that are going to be discarded and end up in the Dumpster. Personally, I have trouble with the ethical argument that it is inappropriate to use these embryos to save lives, but somehow it's appropriate to throw them in the Dumpster. I don't understand that.
What are you hearing from others about Obama's order?
Absolute excitement, enthusiasm, real hope for the future. The years of hard work of keeping this issue alive were worth it. There's a genuine sincere happiness. People are saying, "we've worked so long," and "I've waited for this day for so long." There's great potential for health benefits in so many ways. This has been an issue where researchers and patients have been so closely alignedâtwo groups that don't tend to work together or communicate very much. It's so heartwarming to see that the emotion is just as great on the researchers' side as it is on the patients' side.
Some patients today believe there will be embryonic-stem-cell treatments in their lifetime. Is that realistic?
That is one of the most difficult realities that I've had to accept in this job. I think most patients understand that more research needs to be done. Breakthroughs happen but no one can give a timeline. I have such respect for patient advocates. They understand that even if it doesn't help them, they want to help the next person.
Now that CAMR has achieved its goal, what will you do?
Aside from sleep? Our primary focus was the executive order. Now, NIH will begin working on guidelines for research, so we'll be focused on that. And there's been consistent conversation about legislation to make sure this form of research will continue to remain eligible for federal funding. When that happens, maybe our coalition will go away. That's what should happen when a single-mission organization has succeeded. It would be a wonderful thing.
How do you respond to people who are opposed to the destruction of embryos for medical research?
We have to always remember that the largest source of embryonic stem cells are embryos in IVF clinics that are going to be discarded and end up in the Dumpster. Personally, I have trouble with the ethical argument that it is inappropriate to use these embryos to save lives, but somehow it's appropriate to throw them in the Dumpster. I don't understand that.
What are you hearing from others about Obama's order?
Absolute excitement, enthusiasm, real hope for the future. The years of hard work of keeping this issue alive were worth it. There's a genuine sincere happiness. People are saying, "we've worked so long," and "I've waited for this day for so long." There's great potential for health benefits in so many ways. This has been an issue where researchers and patients have been so closely alignedâtwo groups that don't tend to work together or communicate very much. It's so heartwarming to see that the emotion is just as great on the researchers' side as it is on the patients' side."
http://www.newsweek.com/2009/03/08/a-new-stem-cell-era.html
