There are numerous CTAs trading several billions as already mentioned in this thread, so it seems that it is possible.
However, this comes at a cost:
1) In order to accomodate such large amounts, the focus shifts more and more to financial futures, away from the commodity markets which are not liquid enough anymore. Sure, the energy sector etc. is no problem, however sectors like meats, softs, agriculture are a problem, so on a relative basis they can allocate only a small amount to these markets. Hence, these funds offer less diversification than a smaller CTA.
At times this might even play out in their favor (e.g. if the markets they have a higher allocation to - lets say bonds - have strong trends), but in the long run they should have a lower risk-adjusted return than small- to medium sized CTAs (note that too small leads to different problems).
2) Large part of their research is focused on order execution, i.e. how to handle their huge order sizes. For an investor thats actually bad news as the focus is not on improving the systems but just on how to minimize their market impact when managing such large amounts of money.
3) Another problem (to a smaller degree): Large CTAs have started to trade OTC instruments which is another source of risk.
So I would say that the statement of the CTA you mentioned is only partly true and is certainly not professional.
However, this comes at a cost:
1) In order to accomodate such large amounts, the focus shifts more and more to financial futures, away from the commodity markets which are not liquid enough anymore. Sure, the energy sector etc. is no problem, however sectors like meats, softs, agriculture are a problem, so on a relative basis they can allocate only a small amount to these markets. Hence, these funds offer less diversification than a smaller CTA.
At times this might even play out in their favor (e.g. if the markets they have a higher allocation to - lets say bonds - have strong trends), but in the long run they should have a lower risk-adjusted return than small- to medium sized CTAs (note that too small leads to different problems).
2) Large part of their research is focused on order execution, i.e. how to handle their huge order sizes. For an investor thats actually bad news as the focus is not on improving the systems but just on how to minimize their market impact when managing such large amounts of money.
3) Another problem (to a smaller degree): Large CTAs have started to trade OTC instruments which is another source of risk.
So I would say that the statement of the CTA you mentioned is only partly true and is certainly not professional.