I had done a fellowship at UTA on small molecules in oncology, well that was the emphasis. Chemotherapeutic-resistance (chemoresistance) in refractory tumor models. So those presenting terminal; been through first, second-line therapies. We used CCAs to inhibit cellular p-gp.. There are a couple papers floating around on Academia. Back then the best thing available was Taxotere and the rest were mostly alkylating-agents. Really toxic stuff.
My mom developed MBC/ABC and rec'd lumpectomy/radiation. 10Y later had recurrence and treated with Dox/Cytoxan/5FU. She went into remission but developed chem-induced cardiomyopathy. I had studied CoQ10 and other small molecules at Austin and had a source for ubiquinone (CoQ10) as it was not yet widely available.
My mom's LVEF went from 60 to 12, post-Doxorubicin. She couldn't walk 100 steps but was in remission. I sourced Keneka CoQ10 powder from Austin and they sourced from Kaneka in Japan. I gave her 1-2g a day at huge cost and in three months her LVEF by Acuson hit 62. Her Onco at UChicago had never seen chem-induced CM resolved. They use a protocol developed from her clinicals when Dox/Adriamycin is used.
She was doing great and was advised to start on an adjuvant-cycle of Mitomycin to maintain remission, which is a drug I was violently opposed to (alkylating agent) due to possibility of HUS. Mom developed HUS months later and died shortly thereafter.
I knew that the whole field is a sham. Her Oncologist had some fame but would call a second year med to calc mg/m^2 for patient dosing? He was responsible for mom agreeing to the Mitomycin. It was a tough time as dad died months before. I left school and planned to take out the Onco with a G3, but came to my senses.
As far as these guys blowing themselves over fake wins... I only show time stamped gains bc nobody else will do so. I wouldn't have any cred otherwise.
I'm sure in real life you probably are a really nice guy!