Odds are a shutdown in the US will work no better than it did before, especially given a large proportion of the US population don’t believe in shutdowns, or in PPE for that matter.
Odds are a Covid vaccine will be mostly ineffective, especially on older people or after six months as new Covid strains emerge, just like with influenza.
Covid is now endemic and spreads among various mammals, allowing for additional opportunities for reinfection of humans.
The world had its chance to contain this virus in January through coodinated shutdowns, border closings, and PPE mandates. That chance is over and Covid is here to stay for generations to come.
The market has or will price in this realization soon.
Those who make needed lifestyle changes and possibly undergo genetic testing to determine relative risks for severe outcomes of a Covid infection, will be in a better position to protect themselves.
If the general population of the world make needed lifestyle changes, the resulting increase in productivity could be a net bullish factor for future economic growth.