Quote from Tsing Tao:
Any .22 as a carry weapon is useless. Hell, as any use other than a varmint killer or mob style killing (into the back of the skull), a .22 handgun is worthless. Just my opinion. If you live in colder climates, it's even more worthless. On a winter day, a .22 probably won't even pierce thick layers of jacket and clothing.
I agree. If someone is on drugs and attacking you, it's just going to piss them off if you shoot them with a .22.
We have a few .45's around here, one of them being an actual Colt from WWII. Unbelievably cool gun, but I wouldn't want to carry it on a daily basis. Very bulky and heavy.