Unless they've got a ton of time (99% don't), they'll not be able to get in your safe. Anchoring is smart, as is recessing back into wall. One thing to KNOW is if you're dealing with some serious trash, they'll await you and family to come home, and torture until they get the combination. This is why I have guns in every room in my house, including both garages. Have machetes* stashed all over, and even a few "items" that WILL get their attention, and then some...
I have to laugh. I've got an AR-15 over my fireplace mantel, and it's supposed to be for "looks." Next room, a single action .45 on a western frame. What most wouldn't expect-they're loaded, and ready to use. Ooh rah!
If it's not affordable to outfit guns all over your house (or if kids around), buy machetes! They're absolutely evil! I've seen one used in action vs a human, and..well, no one will fuck with you after you've buried it in their stomach! And yes, it takes me half a day to police up weapons all over the house, then put in safe, when my Nieces and Nephews are due here from out of state. Always better to err on the safe side when kids are around. And again, but some machetes bro! You'll thank me for decades!