"Performance-enhancing substances in adolescent athletes."
I don't think nitro is under 18.
Notice your info in the link is from 2000-2002.
This supplement has been out for 15+ years already. And they have done studies on those who have taken it for 5 years straight with large doses.
http://www.fitnessandlifestyle.co.uk/index.php?showtopic=2102
Also notice I advised not loading it and taking huge amounts like the vendors advise.
Most vendors advise taking 5 grams everyday day for maintenance which is 150 grams roughly a month. I see great results only taking 2 grams only on days right after a workout which equates to only 24 grams a month. I also advise taking it for 4 weeks on and then 4 weeks off.
"Clinical situations, however, do exist where low doses of creatine have been used for several years with no signs of adverse side effects. For example, Gyrate Atrophy is a disease of the eye (retina) that is characterized by progressive narrowing of the visual fields. A secondary component of the disease is a deficiency in creatine synthesis. Consequently, this disease is also characterized by a reduction in the size of fast muscle fibers. Creatine supplementation has been shown to alleviate the muscular symptoms associated with this disease, although the visual symptoms persist. Other than mild weight gain, however, low doses of creatine (1.5 grams/day) when administered for the duration of several years produced no obvious adverse effects."