So you think all of those negative effects will kick in because of one extra rep -- the one that goes to failure? I doubt it. As for stopping just short of failure, that requires some judgment, which, admittedly, someone who's been doing it for a while can reasonably estimate. But going to actual failure removes subjectivity. And I find it relieves the daily stresses of life like nobody's business. But I do agree that you can't do a lot of volume at that kind of intensity.Just go 1 short of failure...virtually all the benefits but none of the side effects of failure. Side effects are primarily massive metabolic stress i.e. lactate, endocrine and ammonia production increase exponentially. Ammonia is toxic to the brain btw....
